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  • (2R)-2-(乙酰氧基)-N-[(1S,2S,3R)-2,3-双(乙酰氧基)-1-[(乙酰氧基)甲基]十七烷基]二十四碳酰胺

    2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate

    (2R)-2-(乙酰氧基)-N-[(1S,2S,3R)-2,3-双(乙酰氧基)-1-[(乙酰氧基)甲基]十七烷基]二十四碳酰胺
    产品编号 CFN98439
    CAS编号 340702-68-3
    分子式 = 分子量 C50H93NO9 = 852.3
    产品纯度 >=98%
    物理属性 Powder
    化合物类型 Cerebrosides
    植物来源 The herbs of Phyllanthus emblica
    ChemFaces的产品在影响因子大于5的优秀和顶级科学期刊中被引用
    提供自定义包装
    产品名称 产品编号 CAS编号 包装 QQ客服
    (2R)-2-(乙酰氧基)-N-[(1S,2S,3R)-2,3-双(乙酰氧基)-1-[(乙酰氧基)甲基]十七烷基]二十四碳酰胺 CFN98439 340702-68-3 1mg QQ客服:3257982914
    (2R)-2-(乙酰氧基)-N-[(1S,2S,3R)-2,3-双(乙酰氧基)-1-[(乙酰氧基)甲基]十七烷基]二十四碳酰胺 CFN98439 340702-68-3 5mg QQ客服:3257982914
    (2R)-2-(乙酰氧基)-N-[(1S,2S,3R)-2,3-双(乙酰氧基)-1-[(乙酰氧基)甲基]十七烷基]二十四碳酰胺 CFN98439 340702-68-3 10mg QQ客服:3257982914
    (2R)-2-(乙酰氧基)-N-[(1S,2S,3R)-2,3-双(乙酰氧基)-1-[(乙酰氧基)甲基]十七烷基]二十四碳酰胺 CFN98439 340702-68-3 20mg QQ客服:3257982914
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    ChemFaces的产品在许多优秀和顶级科学期刊中被引用

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
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  • Korea Food Research Institute(KFRI) (Korea)
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  • 国外学术期刊发表的引用ChemFaces产品的部分文献
  • J Pharm Biomed Anal.2022, 207:114398.
  • Foods. 2022, 11(23):3905.
  • Oncotarget.2017, 8(53):90925-90947
  • Phytomedicine.2018, 38:12-23
  • Biochem Pharmacol.2020, 178:114083
  • Natural Product Res.&Deve.2022, 1001-6880.
  • Nature Ecology & Evolution2020, doi: 10.1038
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  • Toxins (Basel).2020, 12(4):210.
  • Pharmacol Rep.2017, 69(6):1224-1231
  • Biomed Pharmacother.2022, 146:112497.
  • Microorganisms.2021, 9(12):2514.
  • Natural Product Communications2021, 16(9):1-10.
  • Molecules.2020, 25(23):5609.
  • Evid Based Complement Alternat Med.2021, 2021:8707280.
  • Antioxidants (Basel).2021, 10(11): 1802.
  • ACS Synth Biol.2020, 9(9):2282-2290.
  • J Drug Delivery Science and Tech.2022, 67:102957.
  • Nat Prod Commun.2014, 9(5):679-82
  • J Ethnopharmacol.2018, 210:88-94
  • Cell Chem Biol.2019, 26(1):27-34
  • Sci Rep. 2018, 10590
  • Food Chem.2017, 221:1135-1144
  • ...
  • 生物活性
    Description: (2S,3S,4R,2′R )-2-(2′-Hydroxytetracosanoylamino) octadecane-1,3,4-triol at concentration of 100 ug/mL shows selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom, but inactive against PLA 2 of bee venom (Apis mellifcra).
    In vitro:
    Chinese Journal of Organic Chemistry, 2003,23(8): 853-7.
    Chemical Constituents of the Fungus Leccinum extremiorientale[Reference: WebLink]

    METHODS AND RESULTS:
    Thirteen chemical constituents were isolated from the fruiting bodies of basidiomyctes Leccinum extremiorientale, and their structures were elucidated by spectral and physical-chemical data as: ergosta-7,22-dien-3β,5α,6β-triol (1), ergosterol peroxide (2), ergosterol (3), ergosta-4,6,8(14),22-tetraen-3-one (4), ergosta-5,7-dien-3β-ol (5), palmitic acid (6), (2S,3S,4R,2′R)-2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol (7), cerebroside B (8), cerebroside D (9), uracil (10), inosine (11), adeosine (12) and D-allitol (13). The NMR data of compounds 8 and 9 were completely assigned by 2D-NMR techniques, including 1H-1H COSY, HMBC and HMQC.
    CONCLUSIONS:
    Compounds 2, 7 and 8 at concentration of 100 μg/mL showed selectively inhibitory activity against phospholipase A 2 (PLA 2) secreted from Crotalus adamenteus venom, but inactive against PLA 2 of bee venom (Apis mellifcra). In addition, the methanol-chloroform soluble extract of this fungus also showed 67% antifeedant rate against Leucaninia separata and caused 55% mortality against Plutella xylostella after three-day application.
    制备储备液(仅供参考)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.1733 mL 5.8665 mL 11.733 mL 23.4659 mL 29.3324 mL
    5 mM 0.2347 mL 1.1733 mL 2.3466 mL 4.6932 mL 5.8665 mL
    10 mM 0.1173 mL 0.5866 mL 1.1733 mL 2.3466 mL 2.9332 mL
    50 mM 0.0235 mL 0.1173 mL 0.2347 mL 0.4693 mL 0.5866 mL
    100 mM 0.0117 mL 0.0587 mL 0.1173 mL 0.2347 mL 0.2933 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    部分图片展示
    产品名称 产品编号 CAS编号 分子式 = 分子量 位单 联系QQ
    三七草酰胺II; Gynuramide II CFN98367 295803-03-1 C42H83NO5 = 682.1 5mg QQ客服:2056216494
    (2R)-2-(乙酰氧基)-N-[(1S,2S,3R)-2,3-双(乙酰氧基)-1-[(乙酰氧基)甲基]十七烷基]二十四碳酰胺; 2-2'-(Hydroxytetracosanoylamino)-octadecane-1,3,4-triol tetraacetate CFN98439 340702-68-3 C50H93NO9 = 852.3 5mg QQ客服:2159513211
    (2S,3S,4R,2'R)-2-(2'-羟基二十四碳酰氨基)十八烷-1,3,4-三醇; 2-(2'-Hydroxytetracosanoylamino)-octadecane-1,3,4-triol CFN99649 154801-30-6 C42H85NO5 = 684.1 5mg QQ客服:3257982914
    大豆脑苷I; Soyacerebroside I CFN99242 114297-20-0 C40H75NO9 = 714.0 5mg QQ客服:215959384
    大豆脑苷II; Soyacerebroside II CFN99250 115074-93-6 C40H75NO9 = 714.0 5mg QQ客服:1413575084
    Momor-脑苷脂I; Momor-cerebroside I CFN97031 606125-07-9 C48H93NO10 = 844.3 5mg QQ客服:2159513211
    脑苷脂B; Cerebroside B CFN97455 88642-46-0 C41H77NO9 = 728.1 5mg QQ客服:3257982914

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